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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXT1
All Species:
26.36
Human Site:
T296
Identified Species:
48.33
UniProt:
Q16394
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16394
NP_000118.2
746
86255
T296
G
E
D
V
V
L
L
T
T
C
K
H
G
K
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108202
675
74245
R250
S
A
C
P
W
D
A
R
C
E
Q
D
P
G
P
Dog
Lupus familis
XP_539145
746
86191
T296
G
E
D
V
V
L
L
T
T
C
K
H
G
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P97464
746
86289
T296
G
E
D
V
L
L
L
T
T
C
K
H
G
K
D
Rat
Rattus norvegicus
NP_001101455
670
74649
R245
A
S
A
C
P
W
D
R
N
C
E
Q
D
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509292
443
50957
A18
F
L
A
F
N
F
M
A
Y
D
Y
R
E
M
L
Chicken
Gallus gallus
XP_418396
865
98072
T415
G
E
D
V
V
L
L
T
T
C
K
H
G
K
D
Frog
Xenopus laevis
NP_001083782
738
84810
T288
G
E
D
V
V
L
L
T
T
C
K
H
G
K
D
Zebra Danio
Brachydanio rerio
Q5IGR7
741
85103
T291
A
E
D
V
V
L
L
T
T
C
K
H
G
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V730
760
87290
T293
G
R
D
M
V
L
V
T
T
C
R
H
G
K
S
Honey Bee
Apis mellifera
XP_391845
711
82974
D283
K
A
W
R
E
L
Q
D
E
H
C
Q
Q
D
N
Nematode Worm
Caenorhab. elegans
O01704
378
44434
Sea Urchin
Strong. purpuratus
XP_783281
693
79753
D268
D
H
D
N
A
E
F
D
K
F
D
Y
Q
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
43.9
99.1
N.A.
99.3
42.3
N.A.
58
78.2
88.4
83.6
N.A.
54.4
55.6
26.2
52.1
Protein Similarity:
100
N.A.
60.4
99.5
N.A.
99.7
58.7
N.A.
58.9
81
94.2
91.9
N.A.
69.8
70.2
37.4
68.2
P-Site Identity:
100
N.A.
0
100
N.A.
93.3
6.6
N.A.
0
100
100
93.3
N.A.
66.6
6.6
0
6.6
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
13.3
N.A.
6.6
100
100
93.3
N.A.
86.6
13.3
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
16
0
8
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
8
0
0
0
0
8
62
8
0
0
0
0
% C
% Asp:
8
0
62
0
0
8
8
16
0
8
8
8
8
8
47
% D
% Glu:
0
47
0
0
8
8
0
0
8
8
8
0
8
0
0
% E
% Phe:
8
0
0
8
0
8
8
0
0
8
0
0
0
0
0
% F
% Gly:
47
0
0
0
0
0
0
0
0
0
0
0
54
8
8
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
54
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
8
0
47
0
0
54
0
% K
% Leu:
0
8
0
0
8
62
47
0
0
0
0
0
0
0
16
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
0
0
8
8
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
8
16
16
0
0
% Q
% Arg:
0
8
0
8
0
0
0
16
0
0
8
8
0
0
0
% R
% Ser:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
54
54
0
0
0
0
0
0
% T
% Val:
0
0
0
47
47
0
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _